Common oral infections, periodontal diseases and caries, are associated with inflammatory metabolic profiles related to an increased risk of cardiometabolic diseases, a new study by an international team of researchers suggests. Oral infections also predicted future adverse changes in metabolic profiles.

The association between oral infections and adverse metabolic profiles was observed in the Finnish Health 2000/2011 and Parogene study cohorts.

“The observation is novel, since there are only few studies connecting extensive metabolic measures with oral infections, and no earlier prospective studies exist,” says Professor Pirkko Pussinen from the University of Eastern Finland.

Published in Journal of Dental Research, the study also involved researchers from the University of Helsinki, Karolinska Institutet and Medical University of Graz.

La ricerca scientifica ha raggiunto un nuovo traguardo con la recente nascita di una scimmia chimera, caratterizzata da un'elevata percentuale di cellule staminali embrionali (ESC) omologhe. Questo risultato ha importanti implicazioni per la comprensione della pluripotenza delle cellule staminali nei primati e per lo sviluppo delle modifiche genetiche nei primati non umani.
La ricerca, riportata sulla rivista Cell. è stata condotta da un'equipe di scienziati: Jing Cao, Wenjuan Li, Jie Li, Qiang Sun, Miguel A. Esteban e Zhen Liu, grazie alla collaborazione di molti centri di ricerca cinesi: l'Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, CAS Key Laboratory of Primate Neurobiology, State Key Laboratory of Neuroscience, Chinese Academy of Sciences, di Shanghai, il Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, di Yangling, il Laboratory of Integrative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, di Guangzhou, BGI-Research, Hangzhou, Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, CAS Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun.